4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-
7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one
CAS: 491-74-7
Molecular Formula: C24H26O13
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy- - Names and Identifiers
| Name | 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one |
| Synonyms | C10465 Lridin Iridin Irigenin 7-glucoside Irigenin-7-O-β-D-glucopyranoside Irigenin 7-beta-D-glucopyranoside Irigenin-7-O-beta-D-glucopyranoside 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one 5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside 7-(β-D-Glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy- |
| CAS | 491-74-7 |
| InChI | InChI=1/C24H26O13/c1-32-13-5-9(4-11(26)22(13)33-2)10-8-35-12-6-14(23(34-3)19(29)16(12)17(10)27)36-24-21(31)20(30)18(28)15(7-25)37-24/h4-6,8,15,18,20-21,24-26,28-31H,7H2,1-3H3/t15-,18-,20+,21-,24-/m1/s1 |
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy- - Physico-chemical Properties
| Molecular Formula | C24H26O13 |
| Molar Mass | 522.46 |
| Density | 1.558±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 208℃ |
| Boling Point | 833.5±65.0 °C(Predicted) |
| Specific Rotation(α) | +52.1 (c, 0.73 in MeOH) |
| Flash Point | 284.1°C |
| Solubility | Soluble in methanol, soluble in pyridine, DMSO |
| Vapor Presure | 1.85E-29mmHg at 25°C |
| Appearance | Pale yellow or yellow powder |
| pKa | 5.96±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.659 |
| MDL | MFCD28166495 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from shegan. |
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy- - Reference
| Reference Show more | 1. Yang Yawen, Liu Yong, Liu Yu, Du Hongzhi, Liu assembly, Huang Bicheng. Effects of different drying methods on drying characteristics, appearance and effective components of Belamcanda chinensis [J]. Chinese Journal of Traditional Chinese Medicine, 2021,46(02):366-373. 2. Valkω, Kl · ra. "Application of high-performance liquid chromatography based measurements of obesity to model biological distribution." Journal of chromatography A 1037.1-2 (2004): 299-310.https:// doi.org/10.1016/j.chroma.2003.10.084 3. Valkω, Kl · ra. "Application of high-performance liquid chromatography based measurements of lipid model biological distribution." Journal of chromatography A 1037.1-2 (2004): 299-310.https://doi.org/10.1016/j.chroma.2003.10.084 4. [IF=4.411] Jifeng Gu et al."Application of High-Performance Liquid Chromatography Coupled with Linear Ion Trap Quadrupole Orbitrap Mass Spectrometry for Qualitative and Quantitative Assessment of Shejin-Liyan Granule Supplements."Molecules. 2018 Apr;23(4):884 |
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy- - Introduction
7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one, also known as ophiopogonin Ⅰ, is a natural active ingredient extracted from the rhizome of Ophiopogon japonicus. The following is a description of the properties, uses, formulation and safety information of 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one:
Nature:
7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one is white crystalline powder, odorless, slightly bitter. It is soluble in water, but not in ethanol and chloroform.
Use:
7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one has a variety of pharmacological activities and is widely used in the field of traditional Chinese medicine. It is considered to have anti-inflammatory, antioxidant, anti-tumor, cardiovascular protection and other effects. 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one may also be used in the treatment of diabetes, kidney disease, heart disease, and other inflammation-related diseases.
Preparation Method:
The extraction of 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one is usually carried out by water extraction or solvent extraction. The general method is to cut the roots of Ophiopogon japonicus, add water or organic solvent, after extraction, concentration and separation and purification steps, and finally get 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one.
Safety Information:
The current safety research on 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one is limited, but according to available data, it is considered relatively safe. However, individual tolerance to 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one may vary. Before using 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one, it is recommended to consult the advice of a doctor or health professional. At the same time, should follow the dose of use, not suitable for long-term high dose. For pregnant women, lactating women and children, should be used with caution.
Nature:
7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one is white crystalline powder, odorless, slightly bitter. It is soluble in water, but not in ethanol and chloroform.
Use:
7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one has a variety of pharmacological activities and is widely used in the field of traditional Chinese medicine. It is considered to have anti-inflammatory, antioxidant, anti-tumor, cardiovascular protection and other effects. 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one may also be used in the treatment of diabetes, kidney disease, heart disease, and other inflammation-related diseases.
Preparation Method:
The extraction of 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one is usually carried out by water extraction or solvent extraction. The general method is to cut the roots of Ophiopogon japonicus, add water or organic solvent, after extraction, concentration and separation and purification steps, and finally get 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one.
Safety Information:
The current safety research on 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one is limited, but according to available data, it is considered relatively safe. However, individual tolerance to 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one may vary. Before using 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one, it is recommended to consult the advice of a doctor or health professional. At the same time, should follow the dose of use, not suitable for long-term high dose. For pregnant women, lactating women and children, should be used with caution.
Last Update：2024-04-09 21:11:58
Supplier List
Spot supply
Product Name: Lridin Visit Supplier Webpage Request for quotationCAS: 491-74-7
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Lridin Visit Supplier Webpage Request for quotationCAS: 491-74-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Lridin Visit Supplier Webpage Request for quotationCAS: 491-74-7
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Lridin Visit Supplier Webpage Request for quotationCAS: 491-74-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History